Diabetes Information Library 
Your Source For Articles On Diabetes  
Search Articles:
Bookmark Our Site! Free Newsletter | Special Offers | Archives | Diabetic Dictionary  
acetyl l-carnitine
alpha lipoic acid
american diabetes assoc.
bitter melon
blood sugar
blood sugar level
cause of diabetes
diabetes care
diabetes diet
diabetes education
diabetes food
diabetes information
diabetes insipidus
diabetes management
diabetes medication
diabetes mellitus
diabetes menu
diabetes news
diabetes nutrition
diabetes recipe
diabetes research
diabetes statistics
diabetes symptom
diabetes test
diabetes treatment
diabetes type ii
diabetic cake recipe
diabetic complications
diabetic cookie
diabetic cooking
diabetic dessert recipe
diabetic diet
diabetic exchange
diabetic food list
diabetic meal planning
diabetic menu
diabetic neuropathy
diabetic nutrition
diabetic product
diabetic recipe
diabetic retinopathy
diabetic symptom
exchange diet
food exchange
gestational diabetes
gestational diabetes diet
glycemic index
gymnema sylvestre
healthy carbs
hemoglobin a1c
herb for diabetes
high blood sugar
high triglyceride
idiopathic neuropathy
insulin resistance
juvenile diabetes
low blood sugar
low carbohydrate diet
metabolic syndrome
nerve damage
neuropathy symptoms
normal blood sugar level
peripheral neuropathy
preventing neuropathy
pterocarpus marsupium
sign of diabetes
sugar diabetes
symptom juvenile diabetes
syndrome x
type 1 diabetes
type 2 diabetes
type 2 diabetes diet
types of neuropathy
vanadyl sulfate
Printer Friendly Version

Vitamin C: An Efficient Way To Lower Sorbitol Levels

Author: Michael Murray, ND, and Michael Lyon, MD
Source: Beat Diabetes Naturally - The Best Foods, Herbs, Supplements, And Lifestyle Strategies To Optimize Your Diabetes Care

Attempts to prevent sorbitol accumulation with drugs have failed due to severe side effects. In contrast, vitamin C is able to accomplish what these drugs could not - safe and effective inhibition of sorbitol accumulation.

In one study in young adults with type I diabetes, baseline measurement of sorbitol in red blood cells were nearly double in these patients despite "adequate" dietary intakes of vitamin C. Vitamin C supplementation at a dosage of either 100 or 600 mg normalized sorbitol in red blood cells within 30 days. This correction of sorbitol accumulation was independent of changes in diabetic control as monitored by fasting glucose or hemoglobin A1C. In fact, overall diabetic control during the study was moderate to poor, indicating that the effect of vitamin C was not dependent on glucose concentration.

These results indicate that vitamin C may inhibit aldose reductase, the enzyme that converts glucose to sorbitol. A test-tube study was conducted to determine the necessary concentration of vitamin C required to inhibit aldose reductase in red blood cells. 2  At concentrations above 100 micromoles, vitamin C reduced sorbitol production by about 30 percent. Levels between 600 and 900 micromoles reduced sorbitol production by about 50 percent. Are these concentrations of vitamin C attainable with supplementation with vitamin C? Absolutely: in fact, the normal level of vitamin C in the plasma and red blood cells is 40 to 120 micromoles. One of the reasons that we recommend 500 to 1,500 mg of vitamin C daily is to boost blood levels into the higher range to inhibit sorbitol production. Remember that the transport of vitamin C into cells is facilitated by insulin, and as a result many diabetics do not have enough intracellular vitamin C. Therefore, a relative vitamin C deficiency exists in many diabetics despite adequate dietary consumption. Supplementation is required.


Maintain Healthy
Blood Sugar Levels*


Price $33.95

I Feel So Much Better!
"I have been taking Glucobetic and have seen a remarkable difference. I actually am having a normal blood sugar reading everyday without fail. I just wish I had started this product a long time ago. I really do feel so much better - the sluggishness is gone and I feel like my old self again. Thanks !!"** 
  - A. Workman, OK

Product Details


Sleep So Well
60 Capsules

Calm, Restful Sleep*

Price $17.95



Probiotic Digestive Support

Targets Gas, Bloating & DIfficult Digestion*

Price $27.95

Vitalicious Natural Muffins-100 Delicious Calories

Copyright Act Notice                       

*Many of the statements on this web site have not been evaluated by the Food and Drug Administration or other government, research or academic body; any that were are so marked. This information is not intended to diagnose, treat, cure or prevent diabetes or any disease. Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. Not intended to diagnose or prescribe for medical or psychological conditions nor to claim to prevent, treat, mitigate or cure such conditions. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. Any products advertised are from third parties. You should read carefully all product packaging. You should consult with a healthcare professional before starting any diet, exercise or supplementation program. Do not discontinue the use of prescription medication without the approval of your physician.

**Results not typical; your results may vary.

***Recipes provided usually include nutritional information and diabetic exchanges. Not all recipes are appropriate for all people. Please make sure a recipe is appropriate for your meal plan and pay careful attention to serving sizes. User is solely responsible for their use of any content provided.