Source: Universlty of Maryland School of Medicine
People with type 2 diabetes often have low levels of biotin. Biotin may be involved in the synthesis and release of insulin. Preliminary studies in both animals and people suggest that biotin may help improve blood sugar control in those with diabetes, particularly type 2 diabetes. More research in this area would be helpful.
There have been reports of biotin supplements improving the symptoms of peripheral neuropathy for some people who developed this condition from either long-standing diabetes or on-going hemodialysis for kidney failure. Peripheral neuropathy refers to damage to the nerves of the extremities, most commonly the feet and calves. It is as numbness, tingling, burning or strange sensations, and may be accompanied by pain, muscle weakness, and difficulty walking. People who have taken biotin for these purposes tend to notice improvement as early as 1 to 3 months after starting the supplement.
Reference: McCarthy MF. Toward practical prevention of type 2 diabetes. Med Hypotheses 2000;54(5):786-793.